Subretinal Injection: A Review on the Novel Route of Therapeutic Delivery for Vitreoretinal Diseases
نویسندگان
چکیده
منابع مشابه
Subretinal Injection: A Review on the Novel Route of Therapeutic Delivery for Vitreoretinal Diseases.
Compared to intravitreal injection, subretinal injection has more direct effects on the targeting cells in the subretinal space, which provides a new therapeutic method for vitreoretinal diseases, especially when gene therapy and/or cell therapy is involved. To date, subretinal delivery has been widely applied by scientists and clinicians as a more precise and efficient route of ocular drug del...
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15 صفحه اول[Technique of intravitreal drug injection for therapy of vitreoretinal diseases].
Intravitreal injections are the standard technique applied in the treatment of some vitreoretinal diseases. In this paper the technique and complications of intravitreal injections are presented. In summary, the procedure involves various consecutive steps. Initially, days before the treatment topical antibiotics and acetazolamide may be prescribed for reduction of the ocular flora and intraocu...
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PURPOSE The subretinal space, which borders the retinal pigment epithelium (RPE), photoreceptors, and Müller cells, is an ideal location to deliver genetic vectors, morpholino oligos, and nanopharmaceuticals. Unfortunately, materials injected into the space tend to stay localized, and degenerative changes secondary to retinal detachment limit its usefulness. Furthermore, such injection requires...
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ژورنال
عنوان ژورنال: Ophthalmic Research
سال: 2017
ISSN: 0030-3747,1423-0259
DOI: 10.1159/000479157